Hijacking human proteins to better deliver anti-cancer drugs
Powerful molecules can hitch rides on a plentiful human protein and signal tumors to self-destruct, a team of Vanderbilt University engineers found.
Vanderbilt University
Why Protein Structure Matters in Drug Development: Lab Chat with Steven Almo, Ph.D.
http://www.einstein.yu.edu - Using animations and a walk through his lab, Dr. Steven Almo explains in lay terms why protein structure and shape are important in ...
Albert Einstein College of Medicine
IT-CRS 2013 workshop. Prof. Kratz - Albumin-based Drug Delivery Systems in Oncology
Design and Industrial Development of Advanced Drug Delivery Systems . Thematic workshop of Italian Chapter of Controlled Release Society- Pavia, November ...
fdosio
Aldoxorubicin: Clinical Update of an Albumin‐binding Prodrug of Doxorubicin
Speaker: Dr. Felix Kratz, Ph.D., Vice President of Drug Discovery, CytRx Corporation, Drug Discovery Branch, Innovation Center Freiburg, Freiburg i. Breisgau ...
TAUVOD
In Vitro DDI Drug Transporter Studies ADME 101 Webinar: Efflux and Uptake Transporters
Presenter: Andrew Taylor, Ph.D., Services Technical Support Manager Drug transport can be thought of as the AD&E in ADME, as transporters are responsible ...
Sekisui XenoTech
Quantitative and Systems Pharmacology Approaches for the Development of Oncology Drugs
Modelling and simulation of the absorption, distribution, metabolism and elimination (ADME) of a drug, using a mechanistic approach, can help to predict the ...
Certara
Diagnoses and Treatment of Systemic Amyloidosis
City of Hope
Characterization of Cancer-Related Binding Domains with the ProteOn™ XPR36 Biosensor
For more info, visit http://www.bio-rad.com/yt/2/proteonxpr36 A prominent challenge to overcome in the field of combinatorial protein engineering is functional ...
Bio-Rad Laboratories
ADME 101: DMPK and ADME in Drug Development
Presenter: Joanna Barbara, Ph.D., Vice President of Scientific Operations at SEKISUI XenoTech We are pleased to present SEKISUI XenoTech's first ADME 101 ...
Sekisui XenoTech
What’s New in the Simcyp Simulator v17
Conducting clinical trials incurs immense costs. Thus, technologies that inform and complement clinical trials represent a sea change in drug development.
Certara
Gibco ExpressionWorld 2016: Development of a mammalian recombinant protein production suite
Catherine Owczarek, PhD describes how transient protein expression using the FreeStyle 293, Expi293 and ExpiCHO systems have enabled rapid screening, ...
Thermo Fisher Scientific
Keynote - Cancer Immunology (Carl H. June)
Introduction: Steven J. Burakoff, Dean for Cancer Innovation; Lillian and Henry M. Stratton Professor of Cancer Medicine, Icahn School of Medicine at Mount ...
Icahn School of Medicine
How Do We Translate Pre-clinical and Clinical Research into Drug Labeling?
The number of submissions to the FDA involving physiologically-based pharmacokinetic (PBPK) modeling has increased significantly over the past few years.
Certara
Transcriptional Control of Adipose Tissue Phenotype
A Division of Endocrinology, Diabetes and Bone Diseases Grand Rounds presented by Paul Cohen, MD, PhD, Laboratory of Molecular Mechanism, The ...
Icahn School of Medicine
Stem cell culture: Make or break - Find the optimum for your MSCs and PSCs
Presented By: Jessica Wagener, PhD & Nadine Mellies, PhD Speaker Biography: Dr. Jessica Wagener is Application Specialist focusing on Cell Handling at ...
LabRoots
Novel DOAC Reversal Strategies: Update on Best Practices
Earn CME credit: https://www.naccme.com/program/19-mcln-203-2 In this webcast, Drs. Mark A. Munger, Randolph V. Fugit, and Paul P. Dobesh describe the ...
ImedexCME
Using Virtual Twin Technology to Predict Drug Exposure in Individual Patients
The “one-size-fits-all” approach to healthcare is becoming a thing of the past. The new paradigm of precision medicine aims at delivering the right treatment at ...
Certara
Dr Pawan Malhotra – Challenges of Making Drug Against Malaria Parasite
Dr Malhotra who has worked with the malaria parasite, Plasmodium falciparum for more than two decades talks about research from his laboratory on parasite ...
Living Science
Confirmation Tests for Canine Hypothyroidism in the Dog
Description of tests used primarily as confirmation tests following positive screening tests: free thyroxine concentration and measurement of anti-thyroid hormone ...
VetMedAcademy
Inaugural lecture concerning the drug design is given by Dr. Sergey Shityakov at ITMO University
In order to be efficient as a therapeutic agent, CNS (central nervous system) drugs must cross the blood-brain barrier (BBB) and enter into the brain. The existing ...
shityakoff
Introduction to polymer technology - What is relevant for the interventional cardiologist
Objectives: To learn more about the differences between polymers used on current generation drug eluting stent To understand the biologic responses to ...
PCR
OPIOID PHARMACOKINETICS -PHARMACOLOGY SERIES
Part of the Anaesthesiology lectures basic science series, pharmacology section. Hope it helps! OPIOID PHARMACOKINETICS https://youtu.be/FLgXt3pobyU ...
Forever Learning
Development Advice for Gene Therapy Products
It has been and big year for gene therapy. In the past 12 months, three gene therapy products received approval from FDA, and in July 2018, FDA Commissioner ...
Rho
Colistin vs Polymixin B | Dr Pradeep Rangappa
Dr.Pradeep Rangappa
Tools to Empower Your (CAR) NK Cell Research
Presented By: Martha Luevano, Ph.D. Speaker Biography: Martha Luevano is responsible for the research and clinical NK cell product portfolio at Miltenyi Biotec ...
LabRoots
Employing the Protein Corona to Address Dendritic Cells
Prof. Dr. med. Volker Mailänder, Center for Translational Nanomedicine, University Medicine of the Johannes Gutenberg University Mainz (D) 14.
TAUVOD
NACFC 2020 | S06: Gene Editing Technologies for Understanding and Treatment of Disease
Gene editing, the ability to precisely correct CF-causing variants in the CFTR gene, is a key pillar of Path to a Cure. In this symposium, we will explore how gene ...
Cystic Fibrosis Foundation
Advisor Live Webinar: Vancomycin Dosing: From Trough to AUC
The Infectious Disease Society of America (IDSA) Practice Guidelines are changing to recommend dosing vancomycin by measuring the area under the curve ...
Premier Inc.
IL6 in Health and Disease
The IL6 in Health and Disease webcast reviews IL6 signals and IL6-directed therapies for immunological conditions. The IL6 webcast features expert faculty ...
ClevelandClinicCME
Chemistry, Manufacturing Controls (CMC) in an Investigational New Drug (IND) (7/14) REdI 2017
Maria Cecilia Tami and Balajee Shanmugam review the Chemistry, Manufacturing and Controls (CMC) portion of a drug intended for use under an ...
U.S. Food and Drug Administration
Food Allergy (Anvari)
Dr. Sara Anvari discusses the principles of diagnosis and management of food allergy. Presented on September 14, 2020.
ACAAICOLA
Innate and vaccine-generated antibodies against transthyretin amyloid - Brian O'Nuallain
Aging is associated with the aberrant deposition of sticky extracellular aggregates of amyloid polypeptides in tissues and/or organs. The formation of amyloid is ...
SENS Foundation
COVID19 - Mitigation & Support Strategies in Patients with GN or Transplant
GlomCon Special.
Glomerular Disease Study & Trial Consortium
Modeling vascular tube formation in vitro using ScienCell’s 3D culturing kits
Overview: Living cells exist in complex 3-dimensional, multicellular environments under native physiological conditions involving microenvironment-influenced ...
Sciencell Research Laboratories
Idiosyncratic DILI: Selected Updates
The 6th Annual Fenton Schaffner Lecture presented by Naga Chalasani, MD, Indiana University School of Medicine.
Icahn School of Medicine
Fluorescence Guided Resection of High-Grade Glioma: New Developments
Aaron Cohen-Gadol.
The Neurosurgical Atlas by Aaron Cohen-Gadol, M.D.
COVID-19 Insights: Bangladeshi Doctors Use A Drug Combo Successfully
Ivermectin - How Does It Work? Reference book: Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 13e ...
Drbeen Medical Lectures
11/16/18: The End of Hemophilia?
John Sheehan, MD, presents a talk about advances in clinical care for hemophilia. Dr. Sheehan is an Associate Professor in the Division of Hematology, Medical ...
UW Department of Medicine
Caroline Barelle: Immunogenicity determination of Shark VNAR domains aids candidate selection
As next generation biologics such as novel scaffolds, antibody fragments and fusions progress towards the clinic the need to understand and predict potential ...
ProImmune thinkpeptides
The Kidney & HIV: Implications for Treatment, Prevention & Cure
The 44th Solomon A. Berson, MD, Memorial Lecture presented by Christina Wyatt, MD, Associate Professor of Medicine (Nephrology)
Icahn School of Medicine
Why nature chose S1P as a key vascular and immune regulator - July 13th 2020
Tim Hla from Harvard university gives a webinar on "Why nature chose sphingosine-1-phosphate (S1P) as a key vascular and immune regulator? Implications ...
Sphingolipid Biology
Recombinant Enzymes as a Model System for Drug Profiling Studies
Speaker: Christopher Patten, Ph.D., Program Manager / R&D Abstract The majority of current drugs are eliminated by metabolism through one or more of the ...
Corning Life Sciences