Стимуляция поясного пучка при операции на мозге в состоянии бодрствования
Credits: Kelly Bjanki et al. / The Journal of Clinical Investigation, 2019.
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JCI's Conversation with Giants in Medicine: Donald Seldin
We are joined by Donald Seldin from The University of Texas Southwestern Medical School. Seldin served as the chairman of medicine at UT Southwestern for ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Bruce Beutler
A legend within the field of innate immunity, Dr. Bruce Beutler of the University of Texas Southwestern Medical School is best known for two seminal discoveries: ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Bonnie Bassler
Bonnie Bassler of Princeton University and the Howard Hughes Medical Institute has revolutionized the way that we think about microbiology. She elucidated ...
Journal of Clinical Investigation
Vascular stiffness drives metabolic alterations in pulmonary hypertension
Pulmonary hypertension (PH) refers to a collection of vascular diseases that are characterized by increased arterial pressure in the lung, which can ...
Journal of Clinical Investigation
A pharmacological approach to reversing aniridia
Nonsense mutations that lead to PAX6 haploinsufficiency cause congenital aniridia, a panocular condition that results in severe vision defects. Cheryl ...
Journal of Clinical Investigation
Understanding the drivers of granulomatosis with polyangiitis
Granulomatosis with polyangiitis (GPA) is a form of autoimmune vasculitis that is associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCAs) ...
Journal of Clinical Investigation
Journal of Clinical Investigation - Medical Meaning and Pronunciation
https://www.amazon.com/Mosbys-Medical-Dictionary-Mosby/dp/0323414257?&_encoding=UTF8&tag=maturecolors2-20 Journal of Clinical Investigation ...
Medical Dictionary
JCI's Conversations with Giants in Medicine: Elaine Fuchs
Cell biologist Elaine Fuchs of the Rockefeller University is best known for revolutionizing the molecular and genetic study of skin. Her research has shed light on ...
Journal of Clinical Investigation
David Fox, MD - Video Profile
Professor, Internal Medicine Specialties: Rheumatology, Internal Medicine Clinical Interests: Rheumatoid arthritis and systemic lupus erythematosus A member ...
Michigan Medicine
Brain-wide pathway for waste clearance captured by contrast-enhanced MRI
Helene Benveniste of Stony Brook University discusses the use of contrast-enhanced MRI to visualize the glymphatic system, a paravascular pathway that ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Bruce Alberts
Though Bruce Alberts is well known for his work on the biochemistry of DNA replication and as the editor-in-chief of Science, he is also recognizable as the ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Thomas Starzl
Today in the United States, more than 6000 people a year receive a liver transplant, and since liver transplants have begun, over 200000 patients have received ...
Journal of Clinical Investigation
TRACO 2015: Breast Cancer - Clinical Trials
TRACO 2015: Breast Cancer - Clinical Trials Air date: Monday, September 28, 2015, 4:00:00 PM Category: TRACO Runtime: 02:01:58 Description: Breast ...
NIH VideoCast
Alcohol for brain energy: Risks for dependence
Yale researchers have discovered that the brains of chronic heavy drinkers have twice the capacity of those of light drinkers to consume a chemical that may add ...
YaleUniversity
JCI's Conversations with Giants in Medicine: David Nathan
David Nathan, professor at Harvard Medical School and President Emeritus of the Dana-Farber Cancer Institute, is a renowned hematologist with contributions ...
Journal of Clinical Investigation
Foundations of Clinical Research
Angela Kimel provides a brief overview of the clinical research industry and career opportunities in North Carolina including: * What is a clinical trial and how is it ...
BioNetwork
TLR9 activation in nonalcoholic steatohepatitis
Nonalcoholic steatohepatitis (NASH) is the most common liver disease in the US and can lead to cirrhosis, cancer, and death; however, the drivers of NASH ...
Journal of Clinical Investigation
New research could help predict seizures before they happen
A new study has found a pattern of molecules that appear in the blood before a seizure happens. This discovery may lead to the development of an early ...
RCSI
Creating and publishing a scientific masterpiece
JCI Editor at Large Ushma S. Neill provides updated advice on generating a scientific manuscript with maximum impact.
Journal of Clinical Investigation
Endpoints for Pain Clinical Trials: Patient Reported Outcomes
Dr. Robert Edwards describes the current landscape for patient reported outcomes in pain clinical trials.
National Institutes of Health (NIH)
Chilling out and firming up
Brown adipose tissue (BAT), which mediates non-shivering thermogenesis, contributes to whole body energy expenditure and weight regulation in rodents.
Journal of Clinical Investigation
Antioxidant gene delivery protects photoreceptors
The inherited form of blindness retinitis pigmentosa (RP) results in a progressive loss of photoreceptors. RP-associated mutations directly promote the death of ...
Journal of Clinical Investigation
Using proteomics to predict heart disease risk
Atherosclerosis can result in severe outcomes, including heart attack and stroke. The presence of atherosclerotic plaques is one of the first signs of disease; ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Marc Feldmann
Sir Marc Feldmann's research over the last 30 years has focused on the understanding of autoimmune disease, specifically the treatment of rheumatoid arthritis ...
Journal of Clinical Investigation
Mifepristone treatment of alcohol-dependent rats and humans
Alcohol abuse is a major risk factor for morbidity and disability throughout the world, and treatment options are limited for this complex psychiatric condition.
Journal of Clinical Investigation
Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation
In this episode, Vijay Singh and colleagues reveal that Pancreatic lipase-mediated necrosis of visceral fat worsens outcomes in acute pancreatitis.
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Thomas Südhof
The simple fact that you can understand the words on this page, and that you might remember any of this interview tomorrow, is thanks to the simultaneous and ...
Journal of Clinical Investigation
Protecting kidney from fibrosis by enhancing fatty acid oxidation
In this episode, Santiago Lamas and Verónica Miguel explain that strategies based on FAO-GOF may constitute powerful alternatives to combat fibrosis inherent ...
Journal of Clinical Investigation
Opinion on MRD in CLL: routine use or clinical trials?
Measurable residual disease (MRD) is moving into the clinical setting, attracting varying opinions on the method and setting of its use. Here. Kanti Rai, MD, of ...
VJHemOnc – Video Journal of Hematological Oncology
JCI’s Conversations with Giants in Medicine: Huda Zoghbi
Dr. Huda Zoghbi is a pediatric neurologist, a Howard Hughes Medical Institute investigator; a professor in the departments of Pediatrics, Molecular and Human ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Stuart Kornfeld
Dr. Stuart Kornfeld is the David C. and Betty Farrell Distinguished Professor of Medicine at Washington University in St. Louis. He is best known for his work ...
Journal of Clinical Investigation
Battling cholangiocarcinoma with WNT inhibition
Cholangiocarcinoma is a cancer of the bile duct that has a poor prognosis, largely due to it being refractory to available therapies. In this episode, Stuart Forbes ...
Journal of Clinical Investigation
Increased cardiomyocyte proliferation benefit depends on the heart injury
Pathogenic remodeling following heart injury is due, in part, to the limited regenerative capacity of adult cardiomyocytes. Cell cycle induction has been recently ...
Journal of Clinical Investigation
PI Academy ClinicalTrials.Gov: What It Means For You presented by Daniel E. Ford, MD, MPH
This presentation took place on Monday, June 15th 2020 via Zoom. Presented by director of the Institute for Clinical and Translational Research and vice dean ...
WVCTSI
REG3α as a biomarker and therapeutic target for GVHD
Graft-versus-host-disease (GVHD) is a life-threatening complication of allogeneic BM transplantation that affects skin, liver, and the gastrointestinal (GI) tract.
Journal of Clinical Investigation
A Closer Look: Clinical Trials and the PRESIDIO Study
MSU welcomed Dr. Noreen Henig from Kezar Life Sciences for "A Closer Look: Clinical Trials and the PRESIDIO Study." Clinical trials are a key research tool for ...
Myositis Support and Understanding
Immune tolerance-like pathway inhibits repair following white matter injury
White matter injury is associated with neurological dysfunction in a variety of conditions, ranging from cerebral palsy to vascular dementia. Oligodendrocyte ...
Journal of Clinical Investigation
Poly(A)-specific ribonuclease deficiency in patients with dyskeratosis congenita
The inherited disorder dyskeratosis congenita is characterized by short telomeres, mucocutaneous abnormalities, and bone marrow failure. The underlying ...
Journal of Clinical Investigation
Altered abiraterone metabolism in individuals with HSD3B1 variant
Prostate cancer is driven by stimulation of the androgen receptor (AR) with testosterone and the potent metabolite 5α-dihydrotestosterone (DHT); therefore, ...
Journal of Clinical Investigation
Epigenetic targeting improves metabolic defects in obesity-prone mice
Obesity, diabetes, and other metabolic diseases have known underlying genetic causes; however, environmental factors also play an important role in the onset ...
Journal of Clinical Investigation
Insight into helminth-associated susceptibility to tuberculosis
The pulmonary disease tuberculosis (TB) is a global health problem that results from Mycobacterium tuberculosis (Mtb) infection. As parasitic helminth worms ...
Journal of Clinical Investigation
