Salt generates antiinflammatory Th17 cells...- Christina E. Zielinski and Julia Matthias(TranslaTUM)
JCI- The Journal of clinical Investigation Authors's Take A personal perspective on new research in the JCI Topic: Salt generates antiinflammatory Th17 cells but ...
TranslaTUM
Predicting atrial fibrillation after ablation
In this episode, Jasmeet Reyat, Winnie Chua, Larissa Fabritz, and colleagues explain that, building on genomic and experimental findings, low PITX2 in left ...
Journal of Clinical Investigation
Maternal high-fat diet linked to inflammatory outcomes in offspring
Maternal obesity has been associated with adverse outcomes in offspring; however, it is not clear how maternal obesity or high-fat diet (HFD) impart long-term ...
Journal of Clinical Investigation
Journal of Clinical Investigation - Medical Meaning and Pronunciation
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Medical Dictionary
Chilling out and firming up
Brown adipose tissue (BAT), which mediates non-shivering thermogenesis, contributes to whole body energy expenditure and weight regulation in rodents.
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Stephen O'Rahilly
Professor Stephen O'Rahilly's research has led to an increased understanding of the genetic causes of human obesity and insulin resistance. Using modern ...
Journal of Clinical Investigation
JCI’s Conversations with Giants in Medicine: C. Ronald Kahn
C. Ronald (Ron) Kahn of the Joslin Diabetes Center at Harvard Medical School is a physician-scientist who illuminated much of what we appreciate about the ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: "Best Of"
JCI Editor at Large Ushma S. Neill's "best-of" clips from Conversations with Giants in Medicine, 2012-2017.
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Francis Collins
After Francis Collins received his PhD in Physical Chemistry at Yale University and his medical degree at the University of North Carolina, he zeroed in on ...
Journal of Clinical Investigation
Tie1 deficiency limits cancer progression and metastasis
As primary tumor progression to metastasis dramatically increases mortality in patients with cancer, strategies to limit tumor cell growth and spread are of great ...
Journal of Clinical Investigation
Qualitative Research for Public Health and Clinical Investigation
This video is a one-hour lecture that Roberta E. Goldman, PHD delivered as part of the Harvard Catalyst lecture series in 2011. The lecture presents an overview ...
Brown University
Identification of weight loss-mediating liraglutide targets
The type 2 diabetes drug liraglutide is a glucagon-like peptide-1 receptor (GLP-1R) agonist that lowers blood glucose and reduces body weight. Liraglutide is ...
Journal of Clinical Investigation
Blazing the trail for metastasis
The accompanying movie shows the invasion dynamics of breast cancer spheroids in organotypic culture. Spheroids are composed of trailblazer cells, ...
Journal of Clinical Investigation
Kisspeptin in the limbic system
The hormone kisspeptin is essential for reproductive function, an effect that is mediated by its actions in the hypothalamus. Recent studies suggest that ...
Journal of Clinical Investigation
JCI’s Conversations with Giants in Medicine: Griffin Rodgers
Beginning in the mid-1980s, Dr. Griffin Rodgers, Director of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National ...
Journal of Clinical Investigation
Maternal B12 status influences offspring bone mass
The maternal environment not only affects in utero development, but also can dramatically influence postnatal phenotypes. In this episode, Vijay Yadav, Isabel ...
Journal of Clinical Investigation
A metabolic approach for retinal degeneration
Retinitis pigmentosa (RP) is a heterogeneous genetic disorder that is characterized by a progressive loss of photoreceptors that results in deterioration of vision.
Journal of Clinical Investigation
Akademik Yayınları İndirmenin Basit Yolları
Akademik makaleleri indirmenin en basit yolları anlatılmıştır.
LisansüstüYardımcısı
JCI’s Conversations with Giants in Medicine: Eric Olson
Eric Olson's pivotal research in the field of molecular biology has uncovered the mechanisms that control cardiac and skeletal muscle development. His current ...
Journal of Clinical Investigation
Fibronectin variant mediates smooth muscle cell phenotypic switching
In this episode, Anil Chauhan, Manish Jain, and colleagues reveal that smooth muscle cell- specific fibronectin containing an extra domain A mediates ...
Journal of Clinical Investigation
Journal of Clinical Investigation spanish MEANING
TOP LIST HERE: https://www.youtube.com/playlist?list=PLwTXvKHGHam46KJ_waPqG5PPapwi4iz3K Simple Way for people who understand spanish, to know ...
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Gs/Gq signaling switch in β cells underlies the potential of incretins in diabetes
In this episode, Susumu Seino and Okechi S. Oduori explain how persistent depolarization of β-cells leads to Gs to Gq signaling switch, explaining the ...
Journal of Clinical Investigation
Enteroendocrine cells connecting with neurons
The accompanying movie shows a purified enteroendocrine cell and trigeminal (TG) neuron making a connection (Video 1) and an enteroendocrine cell seeking ...
Journal of Clinical Investigation
Understanding the drivers of granulomatosis with polyangiitis
Granulomatosis with polyangiitis (GPA) is a form of autoimmune vasculitis that is associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCAs) ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Tony Fauci
Tony Fauci is the Director of the National Institute of Allergy and Infectious Diseases within the NIH. His work on HIV is at the forefront of infectious disease ...
Journal of Clinical Investigation
Interferon signature in undifferentiated systemic autoinflammatory diseases
In this episode, Raphaela Goldbach-Mansky, Adriana de Jesus, and colleagues use a comprehensive approach to identify autoinflammatory diseases that ...
Journal of Clinical Investigation
What Is The Definition Of Journal of Clinical Investigation - Medical Dictionary Free Online Terms
Visit our website for text version of this Definition and app download. http://www.medicaldictionaryapps.com Subjects: medical terminology, medical dictionary, ...
Medical Dictionary Online
JCI's Conversations with Giants in Medicine: Stuart Orkin
During Stuart Orkin's training as a physician-scientist, he decided to focus on pediatric blood disorders as an area where disease genetics could connect directly ...
Journal of Clinical Investigation
MICAL1 constrains and protects against disease by oxidizing CaMKII
In this episode, Mark Anderson explains that the stereospecific redox status of CaMKII Methionine 308 regulates CaMKII activation and determines physiological ...
Journal of Clinical Investigation
Angiopoietin/Tie2 maintain the flow of Schlemm’s canal
Schlemm's canal is a lymphatic-like vessel in the eye that is critical for proper drainage of aqueous humor. Glaucoma results from increased intraocular pressure ...
Journal of Clinical Investigation
Salt generates antiinflammatory Th17 cells but amplifies pathogenicity
In this episode, Christina Zielinski and Julia Matthias explain that sodium chloride generates anti-inflammatory human Th17 cell responses but is coopted by ...
Journal of Clinical Investigation
Targeting estrogen receptors to prevent binge eating
Binge eating is associated with obesity and depression. This disorder is more prevalent in women, and there is an apparent correlation between low estrogen ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: David Nathan
David Nathan, professor at Harvard Medical School and President Emeritus of the Dana-Farber Cancer Institute, is a renowned hematologist with contributions ...
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Oliver Smithies
Oliver Smithies of the University of North Carolina at Chapel Hill was awarded the 2007 Nobel Prize in Physiology or Medicine for pioneering homologous ...
Journal of Clinical Investigation
Battling cholangiocarcinoma with WNT inhibition
Cholangiocarcinoma is a cancer of the bile duct that has a poor prognosis, largely due to it being refractory to available therapies. In this episode, Stuart Forbes ...
Journal of Clinical Investigation
Exploring presenilin-1-associated familial Alzheimer's disease
Familial Alzheimer's disease (FAD) is an early on-set, hereditary form of neurological disease with variable pathophysiology that is often associated with loss of ...
Journal of Clinical Investigation
Addressing the point of no return for gene therapy
Retinitis pigmentosa (RP) is hereditary retinal degenerative disease that is characterized by progressive loss of photoreceptor function. In human trials, gene ...
Journal of Clinical Investigation
CD163+ macrophages serve pathogenic role in atherosclerosis
Macrophage polarization in response to stimuli within the microenvironment results in heterogeneous populations that can differentially influence disease.
Journal of Clinical Investigation
JCI's Conversations with Giants in Medicine: Thomas Starzl
Today in the United States, more than 6000 people a year receive a liver transplant, and since liver transplants have begun, over 200000 patients have received ...
Journal of Clinical Investigation
Neuroflux sheds light on olfactory sensory neurons
PET allows noninvasive visualization of several physiological, neurochemical, and pharmacological processes within patients. Application of PET in the brain ...
Journal of Clinical Investigation
Unraveling profibrotic pathways in the kidney
Fibrosis is a hallmark of chronic kidney disease that is characterized by accumulation of extracellular matrix and an influx of immune cells. Autophosphorylation ...
Journal of Clinical Investigation
Clinical trial of IL-7 in septic patients
Sepsis is a life-threatening complication of infection that results in over 250000 deaths per year in the United States. There is a strong correlation between ...
Journal of Clinical Investigation
